Publications

To view more articles by Dr. Haeryfar on PubMed, click here.

Selected Publications

Memarnejadian A, Meilleur CE, Shaler CR, Khazaie K, Bennink JR, Schell TD, Haeryfar SM: PD-1 blockade promotes epitope spreading in anticancer CD8+ T cell responses by preventing fratricidal death of subdominant clones to relieve immunodomination. The Journal of Immunology2017 (in press)
Shaler CR, Tun-Abraham ME, Skaro AI, Khazaie K, Corbett AJ, Mele T, Hernandez-Alejandro R, Haeryfar SM: Mucosa-associated invariant T cells infiltrate hepatic metastases in patients with colorectal carcinoma but are rendered dysfunctional within and adjacent to tumor microenvironment. Cancer Immunology, Immunotherapy 2017 (in press)
Zeppa JJ, Kasper KJ, Mohorovic I, Mazzuca DM, Haeryfar SM, McCormick JK: Nasopharyngeal infection by Streptococcus pyogenes requires superantigen-responsive Vβ-specific T cells. Proceedings of the National Academy of Sciences of the United States of America (PNAS) 2017 (in press)
Highlighted in a commentary published in the same journal [Siemens N, Norrby-Teglund A: Shocking superantigens promote establishment of bacterial infection. PNAS 2017 (in press)
Shaler CR, Choi J, Rudak PT, Memarnejadian A, Szabo PA, Tun-Abraham ME, Rossjohn J, Corbett AJ, McCluskey J, McCormick JK, Lantz O, Hernandez-Alejandro R, Haeryfar SM: MAIT cells launch a rapid, robust and distinct hyperinflammatory response to bacterial superantigens and quickly acquire an anergic phenotype that impedes their cognate antimicrobial function: defining a novel mechanism of superantigen-induced immunopathology and immunosuppression. PLOS Biology 2017, 15(6): e2001930 [PMID:28632753]
Commented in: Sandberg JK, et al: Bacterial deception of MAIT cells in a cloud of superantigen and cytokines. PLOS Biology 2017
Featured in The Scientist magazine